Differential Diagnosis of Lower Extremity Enlargement in Pediatric Patients Referred with a Diagnosis of Lymphedema
Identifieur interne : 005461 ( Main/Exploration ); précédent : 005460; suivant : 005462Differential Diagnosis of Lower Extremity Enlargement in Pediatric Patients Referred with a Diagnosis of Lymphedema
Auteurs : Carolyn C. Schook [États-Unis] ; John B. Mulliken ; Steven J. Fishman ; Ahmad I. Alomari ; Frederick D. Grant ; Arin K. GreeneSource :
- Plastic and reconstructive surgery : (1963) [ 0032-1052 ] ; 2011.
Descripteurs français
- Pascal (Inist)
- Wicri :
English descriptors
- KwdEn :
Abstract
Background: There are many causes for a large lower limb in the pediatric age group. These children are often mislabeled as having lymphedema, and incorrect diagnosis can lead to improper treatment. The purpose of this study was to determine the differential diagnosis in pediatric patients referred for lower extremity "lymphedema" and to clarify management. Methods: The authors' Vascular Anomalies Center database was reviewed between 1999 and 2010 for patients referred with a diagnosis of lymphedema of the lower extremity. Records were studied to determine the correct cause for the enlarged extremity. Alternative diagnoses, sex, age of onset, and imaging studies were also analyzed. Results: A referral diagnosis of lower extremity lymphedema was given to 170 children; however, the condition was confirmed in only 72.9 percent of patients. Forty-six children (27.1 percent) had another disorder: microcystic/macrocystic lymphatic malformation (19.6 percent), noneponymous combined vascular malformation (13.0 percent), capillary malformation (10.9 percent), Klippel-Trenaunay syndrome (10.9 percent), hemihypertrophy (8.7 percent), posttraumatic swelling (8.7 percent), Parkes Weber syndrome (6.5 percent), lipedema (6.5 percent), venous malformation (4.3 percent), rheumatologic disorder (4.3 percent), infantile hemangioma (2.2 percent), kaposiform hemangioendothelioma (2.2 percent), or lipofibromatosis (2.2 percent). Age of onset in children with lymphedema was older than in patients with another diagnosis (p = 0.027). Conclusions: "Lymphedema" is not a generic term. Approximately one-fourth of pediatric patients with a large lower extremity are misdiagnosed as having lymphedema; the most commonly confused causes are other types of vascular anomalies. History, physical examination, and often radiographic studies are required to differentiate lymphedema from other conditions to ensure the child is managed appropriately.
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000190
- to stream PascalFrancis, to step Curation: 000768
- to stream PascalFrancis, to step Checkpoint: 000183
- to stream Main, to step Merge: 005505
- to stream Main, to step Curation: 005461
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Differential Diagnosis of Lower Extremity Enlargement in Pediatric Patients Referred with a Diagnosis of Lymphedema</title>
<author><name sortKey="Schook, Carolyn C" sort="Schook, Carolyn C" uniqKey="Schook C" first="Carolyn C." last="Schook">Carolyn C. Schook</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Departments of Plastic and Oral Surgery, Surgery, and Radiology, Vascular Anomalies Center, Children's Hospital Boston, Harvard Medical School</s1>
<s3>USA</s3>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Departments of Plastic and Oral Surgery, Surgery, and Radiology, Vascular Anomalies Center, Children's Hospital Boston, Harvard Medical School</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mulliken, John B" sort="Mulliken, John B" uniqKey="Mulliken J" first="John B." last="Mulliken">John B. Mulliken</name>
</author>
<author><name sortKey="Fishman, Steven J" sort="Fishman, Steven J" uniqKey="Fishman S" first="Steven J." last="Fishman">Steven J. Fishman</name>
</author>
<author><name sortKey="Alomari, Ahmad I" sort="Alomari, Ahmad I" uniqKey="Alomari A" first="Ahmad I." last="Alomari">Ahmad I. Alomari</name>
</author>
<author><name sortKey="Grant, Frederick D" sort="Grant, Frederick D" uniqKey="Grant F" first="Frederick D." last="Grant">Frederick D. Grant</name>
</author>
<author><name sortKey="Greene, Arin K" sort="Greene, Arin K" uniqKey="Greene A" first="Arin K." last="Greene">Arin K. Greene</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">11-0188296</idno>
<date when="2011">2011</date>
<idno type="stanalyst">PASCAL 11-0188296 INIST</idno>
<idno type="RBID">Pascal:11-0188296</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000190</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000768</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000183</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000183</idno>
<idno type="wicri:doubleKey">0032-1052:2011:Schook C:differential:diagnosis:of</idno>
<idno type="wicri:Area/Main/Merge">005505</idno>
<idno type="wicri:Area/Main/Curation">005461</idno>
<idno type="wicri:Area/Main/Exploration">005461</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Differential Diagnosis of Lower Extremity Enlargement in Pediatric Patients Referred with a Diagnosis of Lymphedema</title>
<author><name sortKey="Schook, Carolyn C" sort="Schook, Carolyn C" uniqKey="Schook C" first="Carolyn C." last="Schook">Carolyn C. Schook</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Departments of Plastic and Oral Surgery, Surgery, and Radiology, Vascular Anomalies Center, Children's Hospital Boston, Harvard Medical School</s1>
<s3>USA</s3>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Departments of Plastic and Oral Surgery, Surgery, and Radiology, Vascular Anomalies Center, Children's Hospital Boston, Harvard Medical School</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mulliken, John B" sort="Mulliken, John B" uniqKey="Mulliken J" first="John B." last="Mulliken">John B. Mulliken</name>
</author>
<author><name sortKey="Fishman, Steven J" sort="Fishman, Steven J" uniqKey="Fishman S" first="Steven J." last="Fishman">Steven J. Fishman</name>
</author>
<author><name sortKey="Alomari, Ahmad I" sort="Alomari, Ahmad I" uniqKey="Alomari A" first="Ahmad I." last="Alomari">Ahmad I. Alomari</name>
</author>
<author><name sortKey="Grant, Frederick D" sort="Grant, Frederick D" uniqKey="Grant F" first="Frederick D." last="Grant">Frederick D. Grant</name>
</author>
<author><name sortKey="Greene, Arin K" sort="Greene, Arin K" uniqKey="Greene A" first="Arin K." last="Greene">Arin K. Greene</name>
</author>
</analytic>
<series><title level="j" type="main">Plastic and reconstructive surgery : (1963)</title>
<title level="j" type="abbreviated">Plast. reconstr. surg. : (1963)</title>
<idno type="ISSN">0032-1052</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Plastic and reconstructive surgery : (1963)</title>
<title level="j" type="abbreviated">Plast. reconstr. surg. : (1963)</title>
<idno type="ISSN">0032-1052</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Child</term>
<term>Differential diagnostic</term>
<term>Lower extremity</term>
<term>Lymphedema</term>
<term>Surgery</term>
<term>Treatment</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Lymphoedème</term>
<term>Chirurgie</term>
<term>Diagnostic différentiel</term>
<term>Extrémité inférieure</term>
<term>Enfant</term>
<term>Traitement</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chirurgie</term>
<term>Enfant</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background: There are many causes for a large lower limb in the pediatric age group. These children are often mislabeled as having lymphedema, and incorrect diagnosis can lead to improper treatment. The purpose of this study was to determine the differential diagnosis in pediatric patients referred for lower extremity "lymphedema" and to clarify management. Methods: The authors' Vascular Anomalies Center database was reviewed between 1999 and 2010 for patients referred with a diagnosis of lymphedema of the lower extremity. Records were studied to determine the correct cause for the enlarged extremity. Alternative diagnoses, sex, age of onset, and imaging studies were also analyzed. Results: A referral diagnosis of lower extremity lymphedema was given to 170 children; however, the condition was confirmed in only 72.9 percent of patients. Forty-six children (27.1 percent) had another disorder: microcystic/macrocystic lymphatic malformation (19.6 percent), noneponymous combined vascular malformation (13.0 percent), capillary malformation (10.9 percent), Klippel-Trenaunay syndrome (10.9 percent), hemihypertrophy (8.7 percent), posttraumatic swelling (8.7 percent), Parkes Weber syndrome (6.5 percent), lipedema (6.5 percent), venous malformation (4.3 percent), rheumatologic disorder (4.3 percent), infantile hemangioma (2.2 percent), kaposiform hemangioendothelioma (2.2 percent), or lipofibromatosis (2.2 percent). Age of onset in children with lymphedema was older than in patients with another diagnosis (p = 0.027). Conclusions: "Lymphedema" is not a generic term. Approximately one-fourth of pediatric patients with a large lower extremity are misdiagnosed as having lymphedema; the most commonly confused causes are other types of vascular anomalies. History, physical examination, and often radiographic studies are required to differentiate lymphedema from other conditions to ensure the child is managed appropriately.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
</list>
<tree><noCountry><name sortKey="Alomari, Ahmad I" sort="Alomari, Ahmad I" uniqKey="Alomari A" first="Ahmad I." last="Alomari">Ahmad I. Alomari</name>
<name sortKey="Fishman, Steven J" sort="Fishman, Steven J" uniqKey="Fishman S" first="Steven J." last="Fishman">Steven J. Fishman</name>
<name sortKey="Grant, Frederick D" sort="Grant, Frederick D" uniqKey="Grant F" first="Frederick D." last="Grant">Frederick D. Grant</name>
<name sortKey="Greene, Arin K" sort="Greene, Arin K" uniqKey="Greene A" first="Arin K." last="Greene">Arin K. Greene</name>
<name sortKey="Mulliken, John B" sort="Mulliken, John B" uniqKey="Mulliken J" first="John B." last="Mulliken">John B. Mulliken</name>
</noCountry>
<country name="États-Unis"><noRegion><name sortKey="Schook, Carolyn C" sort="Schook, Carolyn C" uniqKey="Schook C" first="Carolyn C." last="Schook">Carolyn C. Schook</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005461 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005461 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Main |étape= Exploration |type= RBID |clé= Pascal:11-0188296 |texte= Differential Diagnosis of Lower Extremity Enlargement in Pediatric Patients Referred with a Diagnosis of Lymphedema }}
This area was generated with Dilib version V0.6.31. |